I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
Ciclosporin A induces apoptosis and inhibits angiogenesis induced by VEGF.Cyclosporin A is used as dermatologic drug to treat rheumatoid arthritis and prevent skin disorders. It acts as an immunosuppressive agent, which suppresses the immune function. It finds application as an anti-asthmatic drug to treat asthma. It also suppresses the replication of hepatitis C virus genome in cultured hepatocytes.
Staudinger, L. A.; Spano, S. J.; Lee, W. S.; Coelho, N.; Moriarty, T. J.; McCulloch, C. A. Role of discoidin domain receptor 1 in dysregulation of collagen remodeling by cyclosporin A. Int. J. Biochem. Cell Biol. 2015, 62, 80-87.
Petrillo, C.; Cesana, D.; Piras, F.; Bartolaccini, S.; Naldini, L.; Montini, E.; Rudnitski, A. K. Cyclosporin A and Rapamycin Relieve Distinct Lentiviral Restriction Blocks in Hematopoietic Stem and Progenitor Cells. Molecular Therapy 2015, 23 (2), 352-362.
Hazard Statements: H302-H350-H360
Harmful if swallowed. May cause cancer. May damage fertility or the unborn child.
Precautionary Statements: P201-P280-P301+P312a-P308+P313-P405-P501a
Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.