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Mitomycin C is used as a chemotherapeutic agent due to its antitumor activity. It is used to treat upper gastro-intestinal cancers. It serves as an antineoplastic agent which inhibits DNA synthesis and induces apoptosis.
Yan, C.; Kong, D.; Ge, D.; Zhang, Y.; Zhang, X.; Su, C.; Cao, X. Mitomycin C Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes via a Mitochondrial-Mediated Pathway. Cell. Physiol. Biochem. 2015, 35 (3), 1125-1136.
Tai, T. Y. T.; Moster, M. R.; Pro, M. J.; Myers, J. S.; Katz, L. J. Needle Bleb Revision With Bevacizumab and Mitomycin C Compared With Mitomycin C Alone for Failing Filtration Blebs. J. Glaucoma 2015, 24 (4), 311-315.
Hazard Statements: H300-H351
Fatal if swallowed. Suspected of causing cancer.
Precautionary Statements: P201-P280-P301+P310a-P308+P313-P405-P501a
Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.