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4,5',8-Trimethylpsoralen is used for treatment of psoriasis, and as a photochemical crosslinker of DNA used as a probe for nucleic acid structure, used to crosslink DNA onto mica surfaces, mutagenesis of N2 worms.
Aba Losi.; Roberta Bedotti.; Cristiano Viappiani. Time-Resolved Photoacoustics Determination of Intersystem Crossing and Singlet Oxygen Photosensitization Quantum Yields for 4,5',8-Trimethylpsoralen.J. Phys. Chem.1995, 99, (43), 16162-16167.
Kandallu R. Kumaresan.; Muthukumar Ramaswamy.; Anthony T. Yeung. Structure of the DNA interstrand crosslink of 4,5',8-trimethylpsoralen.Biochemistry.1992, 31, (29), 6774-6783.
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P201-P280i-P304+P340-P405-P501a
Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.