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J63226 4,5',8-Trimethylpsoralen, 99%

CAS Number
3902-71-4
Synonyms
Trioxsalen
TMP

Stock No. Size Price ($) Quantity Availability
J63226-03 1g 70.40
J63226-06 5g 280.00
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4,5',8-Trimethylpsoralen, 99%

MDL
MFCD00005010
EINECS
223-459-0

Chemical Properties

Formula
C14H12O3
Formula Weight
228.25
Form
Powder
Melting point
229-231°
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in chloroform

Applications

4,5',8-Trimethylpsoralen is used for treatment of psoriasis, and as a photochemical crosslinker of DNA used as a probe for nucleic acid structure, used to crosslink DNA onto mica surfaces, mutagenesis of N2 worms.

Notes

Keep container tightly closed. Store away from oxidizing agents. Store in cool, dry conditions in well sealed containers.

Literature References

Aba Losi.; Roberta Bedotti.; Cristiano Viappiani. Time-Resolved Photoacoustics Determination of Intersystem Crossing and Singlet Oxygen Photosensitization Quantum Yields for 4,5',8-Trimethylpsoralen.J. Phys. Chem.1995, 99, (43), 16162-16167.

Kandallu R. Kumaresan.; Muthukumar Ramaswamy.; Anthony T. Yeung. Structure of the DNA interstrand crosslink of 4,5',8-trimethylpsoralen.Biochemistry.1992, 31, (29), 6774-6783.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H335-H351

Causes severe skin burns and eye damage. May cause respiratory irritation. Suspected of causing cancer.

Precautionary Statements: P201-P202-P260-P264b-P271-P281-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,9735
Beilstein
221723
Hazard Class
8
Packing Group
I
Harmonized Tariff Code
2932.20
TSCA
Yes
RTECS
LV1576000

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