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MG 132 is used to inhibitor of calpain proteases, a proteasome and NF-κB inhibitor used as a tool for perturbing the proteasome-regulated degradation of intracellular proteins.
Faneng Sun.; Vellareddy Anantharam.; Danhui Zhang.; Calivarathan Latchoumycandane.; Arthi Kanthasamy.; Anumantha G. Kanthasamy. Proteasome inhibitor MG-132 induces dopaminergic degeneration in cell culture and animal models.NeuroToxicology.2006, 27, (5), 807-815.