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60628-96-8 - Bifonazole, 99% - Mycosporan - 1-(alpha,4-Diphenylbenzyl)imidazole - J63253 - Alfa Aesar

J63253 Bifonazole, 99%

CAS Number
60628-96-8
Synonyms
Mycosporan
1-(alpha,4-Diphenylbenzyl)imidazole

Size Price ($) Quantity Availability
1g 41.80
5g 136.00
25g 401.00
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Bifonazole, 99%

MDL
MFCD00865567
EINECS
262-336-6

Chemical Properties

Formula
C22H18N2
Formula Weight
310.39
Form
Powder
Melting point
142°
Solubility
Soluble in DMSO

Applications

Bifonazole is an imidazole antifungal agent and calmodulin antagonist. It causes a reduction in glycolysis and ATP levels in B16 melanoma cells. Bifonazole is an inhibitor of C14orf1. Bifonazole is an imidazole-based anti-fungal agent with broad spectrum activity against many fungi, molds, yeast and some gram-positive bacteria. Bifonazole inhibits ergosterol biosynthetic protein 28 and Cytochrome P450 2B4.

Notes

Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Julia Penso.; Rivka Beitner. Clotrimazole and bifonazole detach hexokinase from mitochondria of melanoma cells. European Journal of Pharmacology. 1998, 342, (1), 113-117.

Maurizio Botta.; Federico Corelli.; Francesco Gasparrini.; Flavia Messina.; Claudia Mugnaini. Chiral Azole Derivatives. 4.1 Enantiomers of Bifonazole and Related Antifungal Agents:? Synthesis, Configuration Assignment, and Biological Evaluation. J. Org. Chem. 2000, 65,(15), 4736-4739.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1213
Harmonized Tariff Code
2933.29
TSCA
No
RTECS
NI3517000

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