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9001-67-6 - Neuraminidase, Clostridium perfringens - Acyl-neuraminyl hydrolase - EC 3.2.1.18 - J63259 - Alfa Aesar

J63259 Neuraminidase, Clostridium perfringens

CAS Number
9001-67-6
Synonyms
Acyl-neuraminyl hydrolase
EC 3.2.1.18

Size Price ($) Quantity Availability
10mg 330.00
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Neuraminidase, Clostridium perfringens

MDL
MFCD00131711
EINECS
232-624-6

Chemical Properties

Form
Lyophilized powder
Solubility
Soluble in water or 10mM phosphate buffer, pH 6.0

Applications

Neuraminidase is used as a hydrolytic enzyme that removes sialic acid from mucoproteins, used in a study to assess binding with human T lymphocytes in sheep pretreated with neuraminidase. It has also been used in a study to investigate the effect of bile salts on the action of hydrolysis by neuraminidase.

Notes

Minimum 0.5 units per mg dry weight. One unit releases one micromole of sialic acid per minute at 37 C and pH 5.0, from bovine submaxillary mucin

Literature References

James L. McDonel. Clostridium perfringens toxins (type A, B, C, D, E).Pharmacology & Therapeutics.1980, 10, (3), 617-655.

Chin-Hsiang Chien,.; Yih-Jyh Shann.; Sheh-Yi Sheu. Site-directed mutations of the catalytic and conserved amino acids of the neuraminidase gene, nanH, of Clostridium perfringens ATCC 10543.Enzyme and Microbial Technology.1996, 19, (4), 267-276.

Other References

Harmonized Tariff Code
3507.90
TSCA
Yes
RTECS
QQ3450000

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