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Tetracaine hydrochloride is a calcium channel protein inhibitor and blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. Tetracaine hydrochloride is an inhibitor of Na+ CP type X α and Na+ CP type IV α. It blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. Tetracaine hydrochloride has been used for studying the pharmacological effects of spinal anesthesia. Tetracaine hydrochloride has also been used as a component of protease digestion buffers.
H. Hauser.; S.A. Penkett.; D. Chapman. Nuclear magnetic resonance spectroscopic studies of procaine hydrochloride and tetracaine hydrochloride at lipidwater interfaces.Biochimica et Biophysica Acta (BBA) - Biomembranes. 1969, 183 (3),466-475 .
Hazard Statements: H301-H319-H334-H317
Toxic if swallowed. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Precautionary Statements: P260-P201-P280g-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.