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136-47-0 - Tetracaine hydrochloride, 98% - 2-(Dimethylamino)ethyl 4-(n-butylamino)benzoate hydrochloride - J63272 - Alfa Aesar

J63272 Tetracaine hydrochloride, 98%

CAS Number
136-47-0
Synonyms
2-(Dimethylamino)ethyl 4-(n-butylamino)benzoate hydrochloride

Size Price ($) Quantity Availability
25g 73.85
100g 156.80
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Tetracaine hydrochloride, 98%

MDL
MFCD00038912
EINECS
205-248-5

Chemical Properties

Formula
C15H24N2O2•HCl
Formula Weight
300.82
Form
Powder
Solubility
Soluble in water at 50mg/ml

Applications

Tetracaine hydrochloride is a calcium channel protein inhibitor and blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. Tetracaine hydrochloride is an inhibitor of Na+ CP type X α and Na+ CP type IV α. It blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. Tetracaine hydrochloride has been used for studying the pharmacological effects of spinal anesthesia. Tetracaine hydrochloride has also been used as a component of protease digestion buffers.

Notes

Store in a cool dry place. Prevent formation of dust.

Literature References

H. Hauser.; S.A. Penkett.; D. Chapman. Nuclear magnetic resonance spectroscopic studies of procaine hydrochloride and tetracaine hydrochloride at lipid—water interfaces.Biochimica et Biophysica Acta (BBA) - Biomembranes. 1969, 183 (3),466-475 .

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H319-H317-H334

Toxic if swallowed. Causes serious eye irritation. May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statements: P285-P261-P280-P301+P310-P305+P351+P338-P342+P311-P363-P304+P341-P405-P501a

In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,9188
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2922.49
TSCA
No
RTECS
DG4900000

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