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58-32-2 - Dipyridamole - J63329 - Alfa Aesar

J63329 Dipyridamole

CAS Number
58-32-2
Synonyms

Size Price ($) Quantity Availability
5g 40.80
25g 124.00
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Dipyridamole

MDL
MFCD00010555
EINECS
200-374-7

Chemical Properties

Formula
C24H40N8O4
Formula Weight
504.63
Form
Powder
Melting point
165-167°
Solubility
Soluble in chloroform, methanol, dilute acids, ethanol. Slightly soluble in water.

Applications

Dipyridamole prevents platelets sticking to the replacement heart valve and causing a blood clot on the valve. It is used to dilate blood vessels in people with peripheral arterial disease and coronary artery disease. This compound has been shown to suppress high glucose-induced osteopontin mRNA expression and protein secretion, as well as inhibit cAMP and cGMP hydrolysis. Research indicates that Dipyridamole is a non-specific nucleoside transport inhibitor with the ability to increase the effects of adenosine in sinoatrial and atrioventricular nodes. Dipyridamole is an inhibitor of ENT1 and ENT2.

Notes

Store in a cool dry place. Keep away from oxidizing agents.

Literature References

H.C. Diener.; L. Cunha.; C. Forbes.; J. Sivenius, P. Smets.; A. Lowenthal. European Stroke Prevention Study 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke.Journal of the Neurological Sciences. 1996, 143 (1-2),1-13 .

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3346
Harmonized Tariff Code
2933.59
TSCA
No
RTECS
KK7450000

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