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65277-42-1 - Ketoconazole, 98% - J63367 - Alfa Aesar

J63367 Ketoconazole, 98%

CAS Number
65277-42-1
Synonyms

Size Price ($) Quantity Availability
5g 133.00
25g 434.00
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Ketoconazole, 98%

MDL
MFCD00058579
EINECS
265-667-4

Chemical Properties

Formula
C26H28Cl2N4O4
Formula Weight
531.43
Form
Powder
Solubility
Soluble in DMSO, ethanol, chloroform, water, and methanol.

Applications

Ketoconazole is used to treat candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. Ketoconazole is an antifungal agent.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Mikihisa Takano.; Risa Hasegawa.; Takeshi Fukuda.; Ryoko Yumoto.; Junya Nagai.; Teruo Murakami. Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells. European Journal of Pharmacology.1998, 358, (3), 289-294.

Nick E Goeders.; Rachel L Peltier.; Glenn F Guerin. Ketoconazole reduces low dose cocaine self-administration in rats.Drug and Alcohol Dependence.1998, 53, (1), 67-77.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H360-H373

Toxic if swallowed. May damage fertility or the unborn child. May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements: P260-P201-P280-P301+P310a-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,5302
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
TK7912300

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