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9002-04-4 - Thrombin, bovine plasma - Factor IIa - EC 3.4.21.5 - J63383 - Alfa Aesar

J63383 Thrombin, bovine plasma

CAS Number
9002-04-4
Synonyms
Factor IIa
EC 3.4.21.5

Size Price ($) Quantity Availability
100kilounits 530.45
500kilounits 1456.00
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Thrombin, bovine plasma

MDL
MFCD00166053
EINECS
232-648-7

Chemical Properties

Form
Powder
Solubility
Reconstitute in 0.9% sodium chloride

Applications

Thrombin is a trypsin-like serine protease involved in a multitude of processes in the human body. Thrombin generation is the result of limited proteolysis of the vitamin K-dependent zymogen prothrombin. Thrombin is the last enzyme in the clotting cascade functioning to cleave fibrinogen to fibrin which forms the fibrin gel of a haemostatic plug or a pathologic thrombus

Notes

Lyophilized from a solution containing glycine, sodium chloride and calcium chloride. Specific activity is in the range of 90-250 NIH units/mg protein

Literature References

Walter Kisiel.; William M. Canfield.; Lowell H. Ericsson.; Earl W. Davie. Anticoagulant properties of bovine plasma protein C following activation by thrombin.Biochemistry.1977, 16, (26), 5824-5831.

Walter Kisiel. Human plasma protein c: isolation, characterization, and mechanism of activation by α-thrombin.J Clin Invest.1979, 64, (3), 761-769..

Other References

Merck
14,9383
Harmonized Tariff Code
3507.90
TSCA
Yes
RTECS
XO8950000

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