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33507-63-0 - Substance P - Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 - J63489 - Alfa Aesar

J63489 Substance P

CAS Number
33507-63-0
Synonyms
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2

Size Price ($) Quantity Availability
1mg 38.10
5mg 148.00
25mg 586.00
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Substance P

MDL
MFCD00076780
EINECS
251-545-8

Chemical Properties

Formula
C63H98N18O13S
Formula Weight
1347.64
Form
Powder
Solubility
Soluble in water, DMSO, and Acetic Acid.

Applications

Substance P is used as a neurokinin NK-1 receptor agonist, neurokinin undecapeptide neurotransmitter and neuromodulator, also used in cancer cell proliferation and that inhibition of this component can induce apoptosis in cancer cells and decrease the steady state of Her2.

Notes

Protect from heat. Store away from oxidizing agents.

Literature References

Fred Lembeck.; Peter Holzer. Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation.Naunyn-Schmiedeberg's Archives of Pharmacology.1979, (2), 175-183.

Lee, Y.; Takami, K.; Kawai, Y.; Girgis, S.; Hillyard, C.J.; MacIntyre, I.; Emson, P.C.; Tohyama, M. Distribution of calcitonin gene-related peptide in the rat peripheral nervous system with reference to its coexistence with substance P.Neuroscience.1985, (4), 1227-1237.

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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