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Antimycin A is used to study the specific sites of reactive oxygen species production in mitochondria isolated from skeletal muscle of chronic obstructive pulmonary disease patients, and its relationship with local oxidative stress induced by exercise.
Tappel, A.L. Inhibition of electron transport by antimycin A, alkyl hydroxy napthoquinones and metal coordination compounds.Biochemical Pharmacology.1960, (4), 289-296.
Shigeru Sakajo.; Nabuko Minagawa.; Tadazumi Komiyama.; Akio Yoshimoto. Molecular cloning of cDNA for antimycin A-inducible mRNA and its role in cyanide-resistant respiration in Hansenula anomala.Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression.1991, (1), 102-108.
Hazard Statements: H300
Fatal if swallowed.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.