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15318-45-3 - Thiamphenicol - J63575 - Alfa Aesar

J63575 Thiamphenicol

CAS Number
15318-45-3
Synonyms

Size Price ($) Quantity Availability
1g 20.81
5g 47.07
25g 188.49
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Thiamphenicol

MDL
MFCD00467983
EINECS
239-355-3

Chemical Properties

Formula
C12H15Cl2NO5S
Formula Weight
356.22
Form
Powder
Solubility
Soluble in acetonitrile or DMF. Slightly soluble in water

Applications

Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literature References

Tomoko Nagata.; Hisao Oka. Detection of Residual Chloramphenicol, Florfenicol, and Thiamphenicol in Yellowtail Fish Muscles by Capillary Gas Chromatography-Mass Spectrometry.J. Agric. Food Chem.1996, (5), 1280-1284.

Franklin A Davis.; Ping Zhou. Asymmetric synthesis of the antibiotic (+)-thiamphenicol using cis-N-(p-toluenesulfinyl)aziridine 2-carboxylic acids.Tetrahedron Letters.1994, (41), 7525-7528.

Other References

Merck
14,9301
Beilstein
2819542
Harmonized Tariff Code
2941.40
TSCA
No
RTECS
AB6680000

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