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J63593 Captopril

CAS Number
62571-86-2
Synonyms
N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline

Stock No. Size Price ($) Quantity Availability
J63593-03 1g 60.00
J63593-06 5g 143.00
J63593-14 25g 502.00
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Captopril

MDL
MFCD00168073
EINECS
263-607-1

Chemical Properties

Formula
C9H15NO3S
Formula Weight
217.29
Form
Powder
Melting point
104-108°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water (160 mg/ml) at 25°C, sesame and corn oils (<1 mg/ml) at 25°C, methanol (>100 mg/ml), ethanol (>100 mg/ml), isopropanol (>100 mg/ml), chloroform (>100 mg/ml), and dichloromethane (>100 mg/ml).

Applications

Captopril has also been shown to inhibit the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density. Captopril demonstrates noncompetitive inhibition of tyrosinase monophenolase activity and competitive inhibition of diphenolase activity

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

Literature References

Andrew S Greene; Sandra L Amaral. Microvascular angiogenesis and the renin-angiotensin system. Current Hypertension Reports. 2002, 4 (1), 56-62 .

N K Hollenberg. Renal implications of angiotensin receptor blockers. American Journal of Hypertension. 2001, 14, 237S-241S.

GHS Hazard and Precautionary Statements

Hazard Statements: H317-H318-H360D

May cause an allergic skin reaction. Causes serious eye damage. May damage the unborn child.

Precautionary Statements: P201-P202-P261-P272-P280g-P281-P302+P352-P305+P351+P338-P308+P313-P310-P333+P313-P363-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Immediately call a POISON CENTER or doctor/physician. If skin irritation or rash occurs: Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,1774
Beilstein
477887
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
UY0550000

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