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Captopril has also been shown to inhibit the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density. Captopril demonstrates noncompetitive inhibition of tyrosinase monophenolase activity and competitive inhibition of diphenolase activity
Andrew S Greene; Sandra L Amaral. Microvascular angiogenesis and the renin-angiotensin system. Current Hypertension Reports. 2002, 4 (1), 56-62 .
N K Hollenberg. Renal implications of angiotensin receptor blockers. American Journal of Hypertension. 2001, 14, 237S-241S.
Hazard Statements: H317-H318-H360D
May cause an allergic skin reaction. Causes serious eye damage. May damage the unborn child.
Precautionary Statements: P201-P202-P261-P272-P280g-P281-P302+P352-P305+P351+P338-P308+P313-P310-P333+P313-P363-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Immediately call a POISON CENTER or doctor/physician. If skin irritation or rash occurs: Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant