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62571-86-2 - Captopril - N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline - J63593 - Alfa Aesar

J63593 Captopril

CAS Number
62571-86-2
Synonyms
N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline

Size Price ($) Quantity Availability
1g 23.61
5g 164.06
25g 575.00
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Captopril

MDL
MFCD00168073
EINECS
263-607-1

Chemical Properties

Formula
C9H15NO3S
Formula Weight
217.29
Form
Powder
Melting point
104-108°
Solubility
Soluble in water (160 mg/ml) at 25°C, sesame and corn oils (<1 mg/ml) at 25°C, methanol (>100 mg/ml), ethanol (>100 mg/ml), isopropanol (>100 mg/ml), chloroform (>100 mg/ml), and dichloromethane (>100 mg/ml).

Applications

Captopril has also been shown to inhibit the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density. Captopril demonstrates noncompetitive inhibition of tyrosinase monophenolase activity and competitive inhibition of diphenolase activity

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

Literature References

Andrew S Greene; Sandra L Amaral. Microvascular angiogenesis and the renin-angiotensin system. Current Hypertension Reports. 2002, 4 (1), 56-62 .

N K Hollenberg. Renal implications of angiotensin receptor blockers. American Journal of Hypertension. 2001, 14, 237S-241S.

GHS Hazard and Precautionary Statements

Hazard Statements: H361-H317-H303

Suspected of damaging fertility or the unborn child. May cause an allergic skin reaction. May be harmful if swallowed.

Precautionary Statements: P201-P261-P280-P281-P312-P363-P308+P313-P321-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. IF exposed or concerned: Get medical advice/attention. Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1774
Beilstein
477887
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
UY0550000

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