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1614-12-6 - 1-Aminobenzotriazole, 98% - 1-Benzotriazolamine - ABT - J63610 - Alfa Aesar

J63610 1-Aminobenzotriazole, 98%

CAS Number
1614-12-6
Synonyms
1-Benzotriazolamine
ABT

Size Price ($) Quantity Availability
250mg 81.00
1g 232.00
5g 822.00
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1-Aminobenzotriazole, 98%

MDL
MFCD00132902

Chemical Properties

Formula
C6H6N4
Formula Weight
134.14
Form
Powder
Melting point
81-85°
Solubility
Soluble in chloroform, DMSO, ethanol or water

Applications

1-Aminobenzotriazole is used as a Suicide inhibitor of cytochrome P450 and chloroperoxidase, an inhibitor of oxidative drug metabolism in biochemical pharmacology and toxicology studies.

Notes

Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Literature References

Elizabeth A. Dierks.; Christopher Davis, S.; Paul R. Ortiz de Montellano. Glu-320 and Asp-323 Are Determinants of the CYP4A1 Hydroxylation Regiospecificity and Resistance to Inactivation by 1-Aminobenzotriazole.Biochemistry.1998, (7), 1839-1847.

Miranda, C.L.; Henderson, M.C.; Buhler, D.R. Evaluation of Chemicals as Inhibitors of Trout Cytochrome P450s.Toxicology and Applied Pharmacology.1998, (2), 237-244.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
607843
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
DM1235000

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