Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

66-76-2 - Dicumarol - Dicoumarol - 3,3'-Methylenebis(4-hydroxycoumarin) - J63634 - Alfa Aesar

J63634 Dicumarol

CAS Number
66-76-2
Synonyms
Dicoumarol
3,3'-Methylenebis(4-hydroxycoumarin)

Size Price ($) Quantity Availability
5g 30.69
25g 68.39
Add to Cart Add to Quote Request View Item

Dicumarol

MDL
MFCD00006857
EINECS
200-632-9

Chemical Properties

Formula
C19H12O6
Formula Weight
336.30
Form
Powder
Melting point
286-289°
Solubility
Soluble in aqueous alkaline solutions, organic bases, 0.1 N NaOH (15 mg/ml), Pyridine (50 mg/ml), chloroform (slightly soluble), and benzene (slightly soluble). Insoluble in water, and alcohols.

Applications

Dicumarol is a natural chemical used as an anticoagulant agents that functions as a vitamin K antagonist and is also a derivative of Coumarin.

Notes

Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Joseph J Cullen; Marilyn M Hinkhouse; Matthew Grady; Andrew W Gaut; Jingru Liu; Yu Ping Zhang; Christine J Darby Weydert; Frederick E Domann; Larry W Oberley. Dicumarol inhibition of NADPH:quinone oxidoreductase induces growth inhibition of pancreatic cancer via a superoxide-mediated mechanism. Cancer Research. 2003, 63 (17),5513-5520.

Kathryn L. Armour et. al. Expression of human FcγRIIIa as a GPI-linked molecule on CHO cells to enable measurement of human IgG binding. Journal of Immunological Methods. 2010, 354 (1), 20-33.

GHS Hazard and Precautionary Statements

Hazard Statements: H372-H302-H411

Causes damage to organs through prolonged or repeated exposure. Harmful if swallowed. Toxic to aquatic life with long lasting effects.

Precautionary Statements: P260-P273-P264-P270-P301+P312-P314-P330-P391-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Get medical advice/attention if you feel unwell. Rinse mouth. Collect spillage. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3090
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2932.20
TSCA
Yes
RTECS
GN7875000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware