Sodium Acetate is used as a buffer in the buffering range of pH 3.6-5.6. And also used in the purification and precipitation of nucleic acids, in protein crystallization, Staining of gels in protein gel electrophoresis and HPLC. Mordant dyeing; DNA microarray studies of E. coli response. Investigation of protein unfolding during reverse phase chromatography. Used in conjunction with sodium carbonate to enhance the activation of freeze-dried subtilisin Carlsberg in organic solvents. As a substrate of acetokinase.