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57808-66-9 - Domperidone - J63681 - Alfa Aesar

J63681 Domperidone

CAS Number
57808-66-9
Synonyms

Size Price ($) Quantity Availability
50mg 50.50
100mg 98.20
500mg 378.00
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Domperidone

MDL
MFCD00069256
EINECS
260-968-7

Chemical Properties

Formula
C22H24ClN5O2
Formula Weight
425.91
Form
Crystalline powder
Melting point
243°
Solubility
Slightly soluble in water.

Applications

Domperidone is used as a Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier. The antidopaminergic effects of Domperidone have been correlated to antiemetic and gastroprokinetic action.

Notes

Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Literature References

Pierre M. Laduron.; Josee E. Leysen. Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity. Biochemical Pharmacology. 1979, 28, (14), 2161-2165.

Jai D. Kohli.; Dana Glock.; Leon I. Goldberg. Selective DA2 versus DA1 antagonist activity of domperidone in the periphery. European Journal of Pharmacology. 1983, 89, (1-2), 137-141.

GHS Hazard and Precautionary Statements

Hazard Statements: H361

Suspected of damaging fertility or the unborn child.

Precautionary Statements: P201-P280-P202-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3418
Harmonized Tariff Code
2933.39
TSCA
No
RTECS
DE2275900

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