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1177-87-3 - Dexamethasone acetate - J63691 - Alfa Aesar

J63691 Dexamethasone acetate

CAS Number
1177-87-3
Synonyms

Size Price ($) Quantity Availability
250mg 52.50
1g 172.00
5g 636.00
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Dexamethasone acetate

MDL
MFCD00027407
EINECS
214-646-8

Chemical Properties

Formula
C24H31FO6
Formula Weight
434.50
Form
Powder
Melting point
240°
Solubility
Soluble at 100 mg/ml in acetone

Applications

Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts of the body. To treat or prevent allergic reactions. As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions. As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It is also used for replacement therapy in adrenal insufficiency and in a screening test for the diagnosis of cushing's syndrome. Dexamethasone Acetate has also been determined to markedly decrease the number of activated macrophages. In addition, Dexamethasone Acetate has been observed to significantly decrease mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

Literature References

Leibowitz HM,; Kupferman A,; Stewart RH,; Kimbrough RL.Evaluation of dexamethasone acetate as a topical ophthalmic formulation. . Am J Ophthalmol. . 1978, 86 (3), 418-23..

Roberts CP,; Murphy AA,; Santanam N,; Parthasarathy S. The effect of RU 486 and related compounds on cultured macrophage differentiation and function. Am J Obstet Gynecol.. 1996, 175 (2), 248-57.

GHS Hazard and Precautionary Statements

Hazard Statements: H317

May cause an allergic skin reaction.

Precautionary Statements: P261-P280g-P363-P321-P333+P313-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2943
Beilstein
2342608
Harmonized Tariff Code
2937.22
TSCA
Yes
RTECS
TU4050000

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