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Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts of the body. To treat or prevent allergic reactions. As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions. As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It is also used for replacement therapy in adrenal insufficiency and in a screening test for the diagnosis of cushing's syndrome. Dexamethasone Acetate has also been determined to markedly decrease the number of activated macrophages. In addition, Dexamethasone Acetate has been observed to significantly decrease mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice.
Leibowitz HM,; Kupferman A,; Stewart RH,; Kimbrough RL.Evaluation of dexamethasone acetate as a topical ophthalmic formulation. . Am J Ophthalmol. . 1978, 86 (3), 418-23..
Roberts CP,; Murphy AA,; Santanam N,; Parthasarathy S. The effect of RU 486 and related compounds on cultured macrophage differentiation and function. Am J Obstet Gynecol.. 1996, 175 (2), 248-57.
Hazard Statements: H317-H361d-H373
May cause an allergic skin reaction. Suspected of damaging the unborn child. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P201-P202-P260-P272-P280g-P281-P302+P352-P308+P313-P333+P313-P363-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF exposed or concerned: Get medical advice/attention. If skin irritation or rash occurs: Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant