Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

51803-78-2 - Nimesulide - N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide - J63699 - Alfa Aesar

J63699 Nimesulide

CAS Number
51803-78-2
Synonyms
N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide

Size Price ($) Quantity Availability
5g 50.68
25g 178.20
Add to Cart Add to Quote Request View Item

Nimesulide

MDL
MFCD00079470
EINECS
257-431-4

Chemical Properties

Formula
C13H12N2O5S
Formula Weight
308.31
Form
Needle-like crystals
Melting point
145-147°
Solubility
Soluble in water (<50 &#181;g/ml), 1:10 DMSO:PBS (pH 7.2) (<200 &#181;g/ml), ethanol (1 mg/ml), DMSO (15 mg/ml), DMF (15 mg/ml), chloroform, dichloromethane, acetone (freely soluble), and 1N NaOH.

Applications

Nimesulide are used for the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea, . Nimesulide was as effective as paracetamol in reducing fever, local pain, and general discomfort. It was effective in reducing pain associated with osteoarthritis, cancer, thrombophlebitis, oral surgery in adults, otorhinolaryngological diseases and traumatic injury. Nimesulide is demonstrated to suppress azoxymethane-induced carcinogenesis.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literature References

Rick Davis,; Rex N. Brogden.Nimesulide, An Update of its Pharmacodynamic and Pharmacokinetic Properties, and Therapeutic Efficacy. Drugs. Drugs, 199448 (3), 431-454.

Alberto Bernaregg. Clinical Pharmacokinetics of Nimesulide. Clinical Pharmacokinetics. 1995, 35 (4), 247-274.

GHS Hazard and Precautionary Statements

Hazard Statements: H301

Toxic if swallowed.

Precautionary Statements: P264-P270-P301+P310-P321-P330-P405-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Specific treatment (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6548
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2935.00
TSCA
No
RTECS
PB0970000

Recommended

  • B20989

    4-Isobutyl-alpha-methylphenylacetic acid, 99%
  • J60355

    Aceclofenac, 99%
  • J60635

    Meloxicam
  • J61772

    Sulindac
  • H60837

    4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide, 97%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware