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153559-49-0 - Bexarotene, 99+% - LGD-1069 - Targretin - J63701 - Alfa Aesar

J63701 Bexarotene, 99+%

CAS Number
153559-49-0
Synonyms
LGD-1069
Targretin

Size Price ($) Quantity Availability
100mg 135.00
300mg 316.00
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Bexarotene, 99+%

MDL
MFCD00932428

Chemical Properties

Formula
C24H28O2
Formula Weight
348.48
Form
Powder
Melting point
220-225°
Solubility
Soluble in DMSO and ethanol

Applications

Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer?s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

Notes

Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Literature References

Matthew N. Lowe.; Greg L. Plosker. Bexarotene. American Journal of Clinical Dermatology. 2000, 1, (4), 245-250.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1194
Harmonized Tariff Code
2916.39
TSCA
No
RTECS
DH6834830

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