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4205-91-8 - Clonidine hydrochloride, 98+% - 2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride - J63707 - Alfa Aesar

J63707 Clonidine hydrochloride, 98+%

CAS Number
4205-91-8
Synonyms
2-(2,6-Dichloroanilino)-2-imidazoline hydrochloride

Size Price ($) Quantity Availability
1g 81.10
5g 283.00
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Clonidine hydrochloride, 98+%

MDL
MFCD00036705
EINECS
224-121-5

Chemical Properties

Formula
C9H9Cl2N3•HCl
Formula Weight
266.55
Form
Powder
Solubility
Soluble in water (50 mg/ml), DMSO (75 mM), methanol, chloroform (slightly), and dehydrated alcohol.

Applications

Clonidine hydrochloride tablets are indicated in the treatment of hypertension. It has found new uses, including treatment of some types of neuropathic pain, opioid detoxification, sleep hyperhidrosis, anaesthetic use, and off-label, to counter the side effects of stimulant medications such as methylphenidate or amphetamine. It is becoming a more accepted treatment for insomnia, as well as for relief of menopausal symptoms. Clonidine(4205-91-8) is increasingly used in conjunction with stimulants to treat attention-deficit hyperactivity disorder (ADHD).

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literature References

Horvath, J S Md; Phippard, A Mb, Bs; Korda, A Md; Henderson-Smart, D J Md; Child, A Md; Tiller, D J Md.Clonidine Hydrochloride-A Safe and Effective Antihypertensive Agent in Pregnancy. Obstetrics & Gynecology. 1985, 66 (5)

Mark C. Houston. Clonidine hydrochloride: Review of pharmacologic and clinical aspects. Progress in cardiovascular disease. 1981 , 23 (5), 337-350.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H330

Toxic if swallowed. Fatal if inhaled.

Precautionary Statements: P260-P284-P301+P310-P304+P340-P320-P330-P310-P405-P403+P233-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2390
Beilstein
4163525
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2933.29
TSCA
No
RTECS
NJ2490000

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