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J63714 Carbenoxolone disodium salt, 97+%

CAS Number
7421-40-1
Synonyms

Stock No. Size Price ($) Quantity Availability
J63714-03 1g 36.80
J63714-06 5g 144.00
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Carbenoxolone disodium salt, 97+%

MDL
MFCD00079043
EINECS
231-044-0

Chemical Properties

Formula
C34H48Na2O7
Formula Weight
614.70
Form
Solid
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in water to 100 mM.

Applications

Carbenoxolone is anti-inflammatory. It is often used as a gap junction inhibitor in neuroscience research. Carbenoxolone is also an inhibitor of the steroid dehydrogenase enzymes 11 β-hydroxysteroid dehydrogenase (human) and 3α, 20 β-hydroxysteroid dehydrogenase (bacterial). It is used for the treatment of digestive tract ulcers, especially in the stomach. Used in the treatment of peptic, mainly gastric, ulcers. It is often used as a gap junction inhibitor in neuroscience research.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from heat.

Literature References

L. Horwich,; R. Galloway.Treatment of gastric ulceration with carbenoxolone sodium: clinical and radiological evaluation.. Br Med J. . 1965 , 2 (5473), 1274-1277..

W. Hausmann,; A. L. Tarnoky. Biochemical Effects Of Short-Term Treatment With Carbenoxolone Disodium. British Journal of Pharmacology and Chemotherapy. 1966, 26 (2) , 412-420.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,1793
Harmonized Tariff Code
2918.99
TSCA
No
RTECS
RK0250000

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