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7421-40-1 - Carbenoxolone disodium salt, 97+% - J63714 - Alfa Aesar

J63714 Carbenoxolone disodium salt, 97+%

CAS Number
7421-40-1
Synonyms

Size Price ($) Quantity Availability
1g 34.40
5g 136.00
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Carbenoxolone disodium salt, 97+%

MDL
MFCD00079043
EINECS
231-044-0

Chemical Properties

Formula
C34H48Na2O7
Formula Weight
614.70
Form
Solid
Solubility
Soluble in water to 100 mM.

Applications

Carbenoxolone is anti-inflammatory. It is often used as a gap junction inhibitor in neuroscience research. Carbenoxolone is also an inhibitor of the steroid dehydrogenase enzymes 11 β-hydroxysteroid dehydrogenase (human) and 3α, 20 β-hydroxysteroid dehydrogenase (bacterial). It is used for the treatment of digestive tract ulcers, especially in the stomach. Used in the treatment of peptic, mainly gastric, ulcers. It is often used as a gap junction inhibitor in neuroscience research.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from heat.

Literature References

L. Horwich,; R. Galloway.Treatment of gastric ulceration with carbenoxolone sodium: clinical and radiological evaluation.. Br Med J. . 1965 , 2 (5473), 1274-1277..

W. Hausmann,; A. L. Tarnoky. Biochemical Effects Of Short-Term Treatment With Carbenoxolone Disodium. British Journal of Pharmacology and Chemotherapy. 1966, 26 (2) , 412-420.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335-H303

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May be harmful if swallowed.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1793
Harmonized Tariff Code
2918.99
TSCA
No
RTECS
RK0250000

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