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J63734 N,N,N',N'-Tetramethylethylenediamine, Electrophoresis Grade

CAS Number
110-18-9
Synonyms
TEMED

Stock No. Size Price ($) Quantity Availability
J63734-AC 25ml 34.50
J63734-AE 100ml 99.80
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N,N,N',N'-Tetramethylethylenediamine, Electrophoresis Grade

MDL
MFCD00008335
EINECS
203-744-6

Chemical Properties

Formula
C6H16N2
Formula Weight
116.21
Form
Liquid
Melting point
-55°
Boiling Point
120-122°
Flash Point
18°(154°F)
Density
0.775
Refractive Index
1.4180
Storage & Sensitivity
Hygroscopic. Ambient temperatures.
Solubility
Soluble in water 10 mg/mL at 20°C.

Applications

N,N,N',N'-Tetramethylethylenediamine is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent. N,N,N',N'-Tetramethylethylenediamine is used as anti-hyperlipidemic, plant growth stimulator, pathogen growth inhibitor, confers plant disease resistance. TEMED is used with ammonium persulfate to catalyze the polymerization of acrylamide when making polyacrylamide gels, used in gel electrophoresis. TMEDA is widely employed as a ligand for metal ions. TEMED can also be a component of Hypergolic propellants. Tetramethylethylenediamine (TEMED) is an essential catalyst for polyacrylamide gel polymerization. TEMED is frequently used with another catalyst, APS, for the preparation of polyacrylamide gels for protein and nucleic acid analysis.

Notes

Hygroscopic. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, copper, mercury, water, moisture.

Literature References

M.D. Rausch,; D.J. Ciappenelli.Organometallic π-complexes XII. The metalation of benzene and ferrocene by n-butyllithium-N,N,N?,N?-tetramethylethylenediamine. Journal of Organometallic Chemistry. 1967, 10(1), 127-136.

Neena Grover,; Nishi Gupta,; Phirtu Singh,; H. Holden Thorp. Studies of electrocatalytic DNA cleavage by oxoruthenium(IV). X-ray crystal structure of [Ru(tpy)(tmen)OH2](ClO4)2 (tmen = N,N,N',N'-tetramethylethylenediamine, tpy = 2,2',2''-terpyridine). Inorg. Chem. 1992, 31(11), 2014-2020.

GHS Hazard and Precautionary Statements

Hazard Statements: H225-H302-H314-H332-H335

Highly flammable liquid and vapour. Harmful if swallowed. Causes severe skin burns and eye damage. Harmful if inhaled. May cause respiratory irritation.

Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,9134
Beilstein
1732991
Hazard Class
3
Packing Group
II
Harmonized Tariff Code
2921.29
TSCA
Yes
RTECS
KV7175000

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