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110-18-9 - N,N,N',N'-Tetramethylethylenediamine, Electrophoresis Grade - TEMED - J63734 - Alfa Aesar

J63734 N,N,N',N'-Tetramethylethylenediamine, Electrophoresis Grade

CAS Number
110-18-9
Synonyms
TEMED

Size Price ($) Quantity Availability
25ml 26.78
100ml 88.48
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N,N,N',N'-Tetramethylethylenediamine, Electrophoresis Grade

MDL
MFCD00008335
EINECS
203-744-6

Chemical Properties

Formula
C6H16N2
Formula Weight
116.21
Form
Liquid
Melting point
-55°
Boiling Point
120-122°
Flash Point
18°(154°F)
Density
0.775
Refractive Index
1.4180
Sensitivity
Hygroscopic
Solubility
Soluble in water 10 mg/mL at 20°C.

Applications

N,N,N',N'-Tetramethylethylenediamine is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent. N,N,N',N'-Tetramethylethylenediamine is used as anti-hyperlipidemic, plant growth stimulator, pathogen growth inhibitor, confers plant disease resistance. TEMED is used with ammonium persulfate to catalyze the polymerization of acrylamide when making polyacrylamide gels, used in gel electrophoresis. TMEDA is widely employed as a ligand for metal ions. TEMED can also be a component of Hypergolic propellants. Tetramethylethylenediamine (TEMED) is an essential catalyst for polyacrylamide gel polymerization. TEMED is frequently used with another catalyst, APS, for the preparation of polyacrylamide gels for protein and nucleic acid analysis.

Notes

Hygroscopic. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, copper, mercury, water, moisture.

Literature References

M.D. Rausch,; D.J. Ciappenelli.Organometallic π-complexes XII. The metalation of benzene and ferrocene by n-butyllithium-N,N,N?,N?-tetramethylethylenediamine. Journal of Organometallic Chemistry. 1967, 10(1), 127-136.

Neena Grover,; Nishi Gupta,; Phirtu Singh,; H. Holden Thorp. Studies of electrocatalytic DNA cleavage by oxoruthenium(IV). X-ray crystal structure of [Ru(tpy)(tmen)OH2](ClO4)2 (tmen = N,N,N',N'-tetramethylethylenediamine, tpy = 2,2',2''-terpyridine). Inorg. Chem. 1992, 31(11), 2014-2020.

GHS Hazard and Precautionary Statements

Hazard Statements: H225-H314-H302-H332

Highly flammable liquid and vapour. Causes severe skin burns and eye damage. Harmful if swallowed. Harmful if inhaled.

Precautionary Statements: P210-P260-P261-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,9134
Beilstein
1732991
Hazard Class
3
Packing Group
II
Harmonized Tariff Code
2921.29
TSCA
Yes
RTECS
KV7175000

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