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N,N,N',N'-Tetramethylethylenediamine is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent. N,N,N',N'-Tetramethylethylenediamine is used as anti-hyperlipidemic, plant growth stimulator, pathogen growth inhibitor, confers plant disease resistance. TEMED is used with ammonium persulfate to catalyze the polymerization of acrylamide when making polyacrylamide gels, used in gel electrophoresis. TMEDA is widely employed as a ligand for metal ions. TEMED can also be a component of Hypergolic propellants. Tetramethylethylenediamine (TEMED) is an essential catalyst for polyacrylamide gel polymerization. TEMED is frequently used with another catalyst, APS, for the preparation of polyacrylamide gels for protein and nucleic acid analysis.
M.D. Rausch,; D.J. Ciappenelli.Organometallic π-complexes XII. The metalation of benzene and ferrocene by n-butyllithium-N,N,N?,N?-tetramethylethylenediamine. Journal of Organometallic Chemistry. 1967, 10(1), 127-136.
Neena Grover,; Nishi Gupta,; Phirtu Singh,; H. Holden Thorp. Studies of electrocatalytic DNA cleavage by oxoruthenium(IV). X-ray crystal structure of [Ru(tpy)(tmen)OH2](ClO4)2 (tmen = N,N,N',N'-tetramethylethylenediamine, tpy = 2,2',2''-terpyridine). Inorg. Chem. 1992, 31(11), 2014-2020.
Hazard Statements: H225-H302-H332-H314
Highly flammable liquid and vapour. Harmful if swallowed. Harmful if inhaled. Causes severe skin burns and eye damage.
Precautionary Statements: P260u-P201-P280a-P304+P340-P405-P501a
Obtain special instructions before use. Wear protective gloves and eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.