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17086-28-1 - Doxycycline monohydrate - J63805 - Alfa Aesar

J63805 Doxycycline monohydrate

CAS Number
17086-28-1
Synonyms

Size Price ($) Quantity Availability
5g 31.90
25g 128.00
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Doxycycline monohydrate

MDL
MFCD02682958

Chemical Properties

Formula
C22H24N2O8•H2O
Formula Weight
462.46 (444.44anhy)
Form
Powder
Melting point
167-168°
Solubility
Soluble in ethanol or methanol. Sparingly soluble in water.Soluble in dilute acids, alkali hydroxides and dimethyl sulfoxide.

Applications

An antimicrobial. Inhibits angiogenesis and reduces lung metastases by inhibiting matrix metalloproteinasesDoxycycline monohydrate acts as an antibiotic, antimicrobial agent and a matrix metalloproteinase inhibitor. It is also used for the treatment of chloroquine-resistant falciparum malaria. Further, it is used to treat a wide variety of bacterial infections, including those that cause acne. In addition to this, it inhibits the bacterial protein synthesis by preventing the interaction of aminoacyl-tRNA and the bacterial ribosome.

Notes

Incompatible with strong oxidizing agents.

Literature References

Wollina, U. Subantimicrobial-dose doxycycline monohydrate in dermatology. Wien. Med. Wochenschr. 2015, 165 (23), 499-503.

Diakou, A.; Di Cesare, A.; Aeriniotaki, T.; Traversa, D. First report of Troglostrongylus brevior in a kitten in Greece. Parasitol. Res. 2014, 113 (10), 3895-3898.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3440
Harmonized Tariff Code
2941.30
TSCA
No

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