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J63805 Doxycycline monohydrate

CAS Number
17086-28-1
Synonyms

Stock No. Size Price ($) Quantity Availability
J63805-06 5g 33.80
J63805-14 25g 135.00
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Doxycycline monohydrate

MDL
MFCD02682958

Chemical Properties

Formula
C22H24N2O8•H2O
Formula Weight
462.46 (444.44anhy)
Form
Powder
Melting point
167-168°
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in ethanol or methanol. Sparingly soluble in water.Soluble in dilute acids, alkali hydroxides and dimethyl sulfoxide.

Applications

An antimicrobial. Inhibits angiogenesis and reduces lung metastases by inhibiting matrix metalloproteinasesDoxycycline monohydrate acts as an antibiotic, antimicrobial agent and a matrix metalloproteinase inhibitor. It is also used for the treatment of chloroquine-resistant falciparum malaria. Further, it is used to treat a wide variety of bacterial infections, including those that cause acne. In addition to this, it inhibits the bacterial protein synthesis by preventing the interaction of aminoacyl-tRNA and the bacterial ribosome.

Notes

Incompatible with strong oxidizing agents.

Literature References

Wollina, U. Subantimicrobial-dose doxycycline monohydrate in dermatology. Wien. Med. Wochenschr. 2015, 165 (23), 499-503.

Diakou, A.; Di Cesare, A.; Aeriniotaki, T.; Traversa, D. First report of Troglostrongylus brevior in a kitten in Greece. Parasitol. Res. 2014, 113 (10), 3895-3898.

GHS Hazard and Precautionary Statements

Hazard Statements: H361d

Suspected of damaging the unborn child.

Precautionary Statements: P201-P202-P281-P308+P313-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use personal protective equipment as required. IF exposed or concerned: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,3440
Harmonized Tariff Code
2941.30
TSCA
No

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