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65710-07-8 - Apramycin sulfate, 96% - J63874 - Alfa Aesar

J63874 Apramycin sulfate, 96%

CAS Number
65710-07-8
Synonyms

Size Price ($) Quantity Availability
1g 101.00
5g 392.00
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Apramycin sulfate, 96%

MDL
MFCD06200257
EINECS
265-890-7

Chemical Properties

Formula
C21H41N5O11•H2SO4
Formula Weight
637.65
Form
Powder
Melting point
168°
Boiling Point
823°
Flash Point
451.6°(845°F)
Density
1.56
Solubility
Soluble in water.

Applications

Potent inhibitor of protein synthesis in bacteria.Apramycin sulfate is used as a potent inhibitor of protein synthesis in bacteria. It acts as an antibacterial agent. It is a useful biochemical for antibiotic and antibacterial research to study antibiotic resistance through protein synthesis inhibition by blocking translocation. It is also essential for clinic in vitro tests known as antimicrobial susceptibility tests to determine their efficacy against certain bacterial species.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.Incompatible with strong oxidizing agents.

Literature References

Zhang, X. Y.; Ding, L. J.; Fan, M. Z. Resistance patterns and detection of aac(3)-IV gene in apramycin-resistant Escherichia coli isolated from farm animals and farm workers in northeastern of China. Res. Vet. Sci. 2009, 87 (3), 449-454.

Haritova, A. M.; Djeneva, H. A.; Lashev, L. D.; Sotirova, P. G.; Gurov, B. I.; Dyankov, V. N. Pharmacokinetics of gentamicin and apramycin in turkeys roosters and hens in the context of pharmacokinetic-pharmacodynamic relationships. J. Vet. Pharmacol. Ther. 2004, 27 (5), 381-384.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H360

Causes skin irritation. Causes serious eye irritation. May damage fertility or the unborn child.

Precautionary Statements: P201-P280-P305+P351+P338-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,752
Harmonized Tariff Code
2941.90
TSCA
No

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