Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

77086-22-7 - Dizocilpine maleate, 99+% - (+)-MK 801 maleate - (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate - J63917 - Alfa Aesar

J63917 Dizocilpine maleate, 99+%

CAS Number
77086-22-7
Synonyms
(+)-MK 801 maleate
(5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate

Size Price ($) Quantity Availability
10mg 82.80
50mg 213.25
Add to Cart Add to Quote Request View Item

Dizocilpine maleate, 99+%

MDL
MFCD00082465
EINECS
278-614-5

Chemical Properties

Formula
C16H15N.C4H4O4
Formula Weight
337.37
Form
Crystalline powder
Solubility
Soluble in ethanol.

Applications

Dizocilpine maleate is used to interact at the NMDA-associated ion channel, preventing Ca2+ flux and blocking NMDA-induced depolarizations. (+)-MK 801 demonstrates potent neuroprotective effects against excitotoxic insult, showing substantial protection against neuron loss produced by NMDA and quinolinic acid introduction.

Notes

Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Literature References

Lannes, B.; Bernard, V.; Bloch, B.; Micheletti, G. Chronic treatment with dizocilpine maleate increases the number of striatal neurons expressing the D2 receptor gene. Neuroscience. 1995, 65, (2), 431-438.

Salin, P.; Nieoullon, A.; Kerkerian-Le Goff, L. Reversal of the adaptive response of neuropeptide Y neurons in the rat striatum to nigrostriatal dopamine deafferentation by theN-methyl-d-aspartate antagonist dizocilpine maleate. Neuroscience. 1994, 61, (1), 93-105.

Other References

Merck
14,3386
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
HP1093575

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware