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75695-93-1 - Isradipine, 98+% - PN 200-110 - J63920 - Alfa Aesar

J63920 Isradipine, 98+%

CAS Number
75695-93-1
Synonyms
PN 200-110

Size Price ($) Quantity Availability
10mg 99.00
50mg 408.00
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Isradipine, 98+%

MDL
MFCD00153820

Chemical Properties

Formula
C19H21N3O5
Formula Weight
371.39
Form
Crystalline powder
Solubility
Soluble in DMSO

Applications

Isradipine is a L-type calcium channel blocker, Isradipine has anti-atherosclerotic effects in animals and improves endothelium-mediated nitric oxide (NO)-dependent vasodilation in vitro. Additional studies indicate that Isradipine may provide a neuroprotective effect in a rat model of focal ischemia and that Isradipine produces a dose-dependent sparing of dopamine neuronal fibers and cell bodies.

Notes

Protect from heat. Store away from oxidizing agents.

Literature References

Zuhlke, R.D.; Bouron, A.; Soldatov, N.M.; Reuter, H. Ca2+ channel sensitivity towards the blocker isradipine is affected by alternative splicing of the human α1C subunit gene. FEBS Letters. 1998, 427, (2), 220-224.

Martine Leroueil-Le Verger.; Laurence Fluckiger.; Young-Il Kim.; Maurice Hoffman.; Philippe Maincent. Preparation and characterization of nanoparticles containing an antihypertensive agent. European Journal of Pharmaceutics and Biopharmaceutics. 1998, 46, (2), 137-143.

Other References

Merck
14,5240
Harmonized Tariff Code
2934.99
TSCA
No

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