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76095-16-4 - Enalapril maleate salt - J63932 - Alfa Aesar

J63932 Enalapril maleate salt

CAS Number
76095-16-4
Synonyms

Size Price ($) Quantity Availability
5g 217.00
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Enalapril maleate salt

MDL
MFCD00133304
EINECS
278-375-7

Chemical Properties

Formula
C20H28N2O5.C4H4O4
Formula Weight
492.52
Form
Powder
Melting point
143-145°
Solubility
Soluble in water, methanol, and ethanol.

Applications

Enalapril maleate salt is used as a long-acting ACE inhibitor and antihypertensive, used to study diabetic angiopathy in diabetic rats and inhibition of ACE in hog plasma (I50=1.2nM). ACE inhibitors disturb the enin-angiotensin- aldosterone system. Additional ACE inhibitors include: Enalapril, Enalaprilat dihydrate, Enalaprilat, and Enalapril-d5 Maleate Salt, among others.

Notes

Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Literature References

Sunny Piyush Bhardwaj.; Saranjit Singh. Study of forced degradation behavior of enalapril maleate by LC and LC-MS and development of a validated stability-indicating assay method. Journal of Pharmaceutical and Biomedical Analysis. 2008, 46, (1), 113-120.

Matthew J. Wyvratt.; Edward W. Tristram.; Theodore J. Ikeler.; Nancy S. Lohr.; Henry Joshua.; James P. Springer.; Byron H. Arison.; Arthur A. Patchett. Reductive amination of ethyl 2-oxo-4-phenylbutanoate with L-alanyl-L-proline. Synthesis of enalapril maleate. J. Org. Chem. 1984, 49, (15), 2816-2819.

GHS Hazard and Precautionary Statements

Precautionary Statements: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3567
Harmonized Tariff Code
2933.99
TSCA
No
RTECS
TW3666000

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