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Magnesium sulfate is applied in replacement therapy for hypomagnesemia. It can be used orally as a laxative to relieve occasional constipation, and to treat low levels of magnesium. It works by replacing magnesium in the body and increasing water in the intestines. It is the first-line antiarrhythmic agent for torsades de pointes in cardiac arrest under the 2005 ECC guidelines and for managing quinidine-induced arrhythmias. It is effective in decreasing the risk that pre-eclampsia progresses to eclampsia.
Andrea G.Witlina, (DO); Baha M.Sibai, MD. Magnesium sulfate therapy in preeclampsia and eclampsia. Obstetrics & Gynecology. 1998, 92,(5), 883-889.
Scott W.Snyder, MD; Michael S.Cardwell, MD. Neuromuscular blockade with magnesium sulfate and nifedipine. American Journal of Obstetrics and Gynecology. 1989, 161,(1), 35-36.