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53885-35-1 - Ticlopidine hydrochloride - 5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride - J63971 - Alfa Aesar

J63971 Ticlopidine hydrochloride

CAS Number
53885-35-1
Synonyms
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride

Size Price ($) Quantity Availability
5g 52.50
25g 171.00
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Ticlopidine hydrochloride

MDL
MFCD00079606
EINECS
258-837-4

Chemical Properties

Formula
C14H14ClNS•HCl
Formula Weight
300.25
Form
Powder
Solubility
Soluble to 100 mM in water and to 100 mM in DMSO.

Applications

Ticlopidine hydrochloride is a selective P2Y12 receptor antagonist. It inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

B.Bergamasco; P.Benna; A.Carolei; M.Rasura; G.Rudelli; C.Fieschi. A randomized trial comparing ticlopidine hydrochloride with indobufen for the prevention of stroke in high-risk patients (TISS Study). Ticlopidine Indobufen Stroke Study. Functional Neurology. 1997, 12,(1), 33-43.

 

J.Shah, PhD; A.Fratis, MA; D.Ellis, MD, PhD; S.Murakami, BS; P.Teitelbaum , PhD. Effect of food and antacid on absorption of orally administered ticlopidine hydrochloride. The Journal of Clinical Pharmacology. 1990, 30,(8), 733-736.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,9429
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
XJ9089100

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