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19767-45-4 - 2-Mercaptoethane sulfonic acid sodium salt, 96% - Coenzyme M sodium salt - MESNA - J63989 - Alfa Aesar

J63989 2-Mercaptoethane sulfonic acid sodium salt, 96%

CAS Number
19767-45-4
Synonyms
Coenzyme M sodium salt
MESNA

Size Price ($) Quantity Availability
10g 81.00
25g 176.80
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2-Mercaptoethane sulfonic acid sodium salt, 96%

MDL
MFCD00007535
EINECS
243-285-9

Chemical Properties

Formula
C2H6NaO3S2
Formula Weight
164.18
Form
Powder
Solubility
Soluble in water. Also soluble in methanol, DMSO (33 mg/ml) and ethanol (<1 mg/ml).

Applications

2-Mercaptoethane sulfonic acid sodium salt is used as an adjuvant in cancer chemotherapy involving cyclophosphamide and ifosfamide. It is used as an antioxidant and cytoprotective agent in a wide variety of applications from protection from toxicity of therapeutic agents, such as cyclophosphamide to prevention from brain injury damage.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

Ariela Marshall; Cindy McGrath; Drew Torigian; Nicholas Papanicolaou; Priti Lal; Carol Kaplan Tweed. Low-dose cyclophosphamide associated with hemorrhagic cystitis in a breast cancer patient. Breast Journal. 2012, 18,(3), 272-275.

 

Nicole J.Look Hong; Francis J.Hornicek; David C.Harmon; Edwin Choy; Yen-Lin Chen; Sam S.Yoon; G.Petur Nielsen; Jackie Szymonifka; Beow Y.Yeap; Thomas F.DeLaney; John T.Mullen. Neoadjuvant chemoradiotherapy for patients with high-risk extremity and truncal sarcomas: A 10-year single institution retrospective study. European Journal of Cancer. 2013, 49,(4), 875-883.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335-H303

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May be harmful if swallowed.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,5909
Beilstein
3657828
Harmonized Tariff Code
2930.90
TSCA
No
RTECS
KI7968000

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