Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

25316-40-9 - Doxorubicin hydrochloride - 14-Hydroxydaunomycin - J64000 - Alfa Aesar

J64000 Doxorubicin hydrochloride

CAS Number
25316-40-9
Synonyms
14-Hydroxydaunomycin

Size Price ($) Quantity Availability
10mg 167.00
50mg 352.00
Add to Cart Add to Quote Request View Item

Doxorubicin hydrochloride

MDL
MFCD00077757
EINECS
246-818-3

Chemical Properties

Formula
C27H29NO11•HCl
Formula Weight
579.99
Form
Solid
Melting point
216° dec.
Solubility
Soluble in water.

Applications

Antitumor antibiotic agent that inhibits DNA topoisomerase II.Doxorubicin hydrochloride is used as an antineoplastic, antibiotic agent that inhibits DNA topoisomerase. It also inhibits nucleic acid synthesis and induces apoptosis. It posses fluorescent property, which enable it for the measurement of drug efflux pump activities and the role of subcellular organelles (golgi and lysosome) in the sequestration of drugs.

Notes

Moisture and light sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Literature References

Benival, D. M.; Devarajan, P. V. In Situ Lipidization as a New Approach for the Design of a Self Microemulsifying Drug Delivery System (SMEDDS) of Doxorubicin Hydrochloride for Oral Administration. J. Biomed. Nanotechnol. 2015, 11 (5), 913-922.

Esmaeili, A.; Hadad, N. A. Preparation of ZnFe2O4-chitosan-doxorubicin hydrochloride nanoparticles and investigation of their hyperthermic heat-generating characteristics. Ceram. Int. 2015, 41 (6), 7529-7535.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H350

Harmful if swallowed. May cause cancer.

Precautionary Statements: P201-P280-P301+P312a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3439
Beilstein
4229251
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
QI9295900

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware