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Antitumor antibiotic agent that inhibits DNA topoisomerase II.Doxorubicin hydrochloride is used as an antineoplastic, antibiotic agent that inhibits DNA topoisomerase. It also inhibits nucleic acid synthesis and induces apoptosis. It posses fluorescent property, which enable it for the measurement of drug efflux pump activities and the role of subcellular organelles (golgi and lysosome) in the sequestration of drugs.
Benival, D. M.; Devarajan, P. V. In Situ Lipidization as a New Approach for the Design of a Self Microemulsifying Drug Delivery System (SMEDDS) of Doxorubicin Hydrochloride for Oral Administration. J. Biomed. Nanotechnol. 2015, 11 (5), 913-922.
Esmaeili, A.; Hadad, N. A. Preparation of ZnFe2O4-chitosan-doxorubicin hydrochloride nanoparticles and investigation of their hyperthermic heat-generating characteristics. Ceram. Int. 2015, 41 (6), 7529-7535.
Hazard Statements: H302-H350
Harmful if swallowed. May cause cancer.
Precautionary Statements: P201-P280-P301+P312a-P308+P313-P405-P501a
Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.