Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

DiO-Lipoprotein, low density, acetylated, human plasma, BT-925 - 3,3'-Dioctadecyloxacarbocyanine-acetylated low density lipoprotein - DiO-Ac-LDL - J64029 - Alfa Aesar

J64029 DiO-Lipoprotein, low density, acetylated, human plasma, BT-925

CAS Number
Synonyms
3,3'-Dioctadecyloxacarbocyanine-acetylated low density lipoprotein
DiO-Ac-LDL

Size Price ($) Quantity Availability
200microg 188.00
Add to Cart Add to Quote Request View Item

DiO-Lipoprotein, low density, acetylated, human plasma, BT-925

Chemical Properties

Form
Liquid
Sensitivity
Light Sensitive

Applications

Labels both vascular endothelial cells and macrophages. It can be used to identify and/or isolate these cells from mixed cell populations. When cells are labeled with DiO-Ac-LDL, the lipoprotein is degraded by lysosomal enzymes and the fluorescent probe accumulates in the intracellular membranes. Labeling cells with DiO-Ac-LDL has no effect on cell viability. Pure cultures of vascular endothelial cells can be isolated from complex primary cultures using fluorescent activated cell sorting.DiO-Lipoprotein, low density, acetylated, human plasma is useful for fixed wavelength fluorescence activated cell sorting (FACS) Cell sorters.

Notes

Store at 4°C. Stable for 3 months.Light sensitive. Store in a cool place. Incompatible with oxidizing agents, light and heat.

Literature References

Ferri, N.; Tibolla, G.; Pirillo, A.; Cipollone, F.; Mezzetti, A.; Pacia, S.; Corsini, A.; Catapano, A. L. Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels. Atherosclerosis 2012, 220 (2), 381-386.

Okura, H.; Saga, A.; Fumimoto, Y.; Soeda, M.; Moriyama, M.; Moriyama, H.; Nagai, K.; Lee, C. M.; Yamashita, S.; Ichinose, A.; Hayakawa, T.; Matsuyama, A. Transplantation of Human Adipose Tissue-Derived Multilineage Progenitor Cells Reduces Serum Cholesterol in Hyperlipidemic Watanabe Rabbits. Tissue Eng. Part C Methods 2011, 17 (2), 145-154.

GHS Hazard and Precautionary Statements

Precautionary Statements: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2937.19
TSCA
No

Recommended

  • 10660

    Cadmium carbonate, Puratronic®, 99.998% (metals basis)
  • 38479

    Sodium chloride crystal optic rectangle, 41mm x 23mm x 6mm, polished both sides
  • A10971

    4-Hydroxyphenylacetonitrile, 97%
  • H50749

    5-Fluoro-N-methyl-2-phenoxybenzylamine, 97%
  • H65434

    2,4-Diaminothiazole hydrochloride, 95%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware