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2392-39-4 - Dexamethasone 21-phosphate disodium salt, 98% - J64083 - Alfa Aesar

J64083 Dexamethasone 21-phosphate disodium salt, 98%

CAS Number
2392-39-4
Synonyms

Size Price ($) Quantity Availability
1g 103.00
5g 321.00
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Dexamethasone 21-phosphate disodium salt, 98%

MDL
MFCD00079105
EINECS
219-243-0

Chemical Properties

Formula
C22H28FNa2O8P
Formula Weight
516.40
Form
Powder
Melting point
233-240°
Solubility
Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane.

Applications

Dexamethasone 21-phosphate disodium salt acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter. It is used in the treatment of emetic effects of cancer therapy and epicondylitis. Further, it serves as an activator of food, medicine, glucocorticoid and anti inflammatory.

Notes

Hygroscopic. Incompatible with oxidizing agents.

Literature References

Keeler, G. D.; Durdik, J. M.; Stenken, J. A. Effects of delayed delivery of dexamethasone-21-phosphate via subcutaneous microdialysis implants on macrophage activation in rats. Acta Biomater. 2015, 23, 27-37.

Ogawa, N.; Kanki, K.; Honda, K.; Tomooka, Y.; Ryoke, K.; Watanabe, T. Involvement of glucocorticoid in induction of lingual T1R3 in rodents. Eur. J. Pharmacol. 2015, 761, 262-267.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H351-H361

Harmful if swallowed. Suspected of causing cancer. Suspected of damaging fertility or the unborn child.

Precautionary Statements: P201-P280-P301+P312a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2943
Beilstein
6473066
Harmonized Tariff Code
2937.22
TSCA
Yes
RTECS
TU4056000

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