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Chlorpropamide is used in the treatment of diabetes metilus type 2. It acts to increase the secretion of insulin and is not effective in patients who do not have pancreatic beta cell function.
Arnold M.Moses; Patricia Numann ; Myron Miller. Mechanism of chlorpropamide-induced antidiuresis in man: Evidence for release of ADH and enhancement of peripheral action. Metabolism. 1973, 22,(1), 59-66.
R.D.Leslie; D.A.Pyke. Chlorpropamide-alcohol flushing: a dominantly inherited trait associated with diabetes. Br Med J. 1978, 2,(6151), 1519-1521.
Hazard Statements: H312-H332-H351
Harmful in contact with skin. Harmful if inhaled. Suspected of causing cancer.
Precautionary Statements: P201-P202-P261-P271-P281-P302+P352-P304+P340-P308+P313-P312-P363-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant