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94-20-2 - Chlorpropamide - 1-(4-Chlorobenzenesulfonyl)-3-n-propylurea - J64110 - Alfa Aesar

J64110 Chlorpropamide

CAS Number
94-20-2
Synonyms
1-(4-Chlorobenzenesulfonyl)-3-n-propylurea

Size Price ($) Quantity Availability
25g 63.35
100g 203.72
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Chlorpropamide

MDL
MFCD00079004
EINECS
202-314-5

Chemical Properties

Formula
C10H13ClN2O3S
Formula Weight
276.74
Form
Powder
Solubility
Soluble in ethanol (1:12), acetone (1:5), chloroform (1:9) and solutions of alkali hydroxides. Does not mix well with water.

Applications

Chlorpropamide is used in the treatment of diabetes metilus type 2. It acts to increase the secretion of insulin and is not effective in patients who do not have pancreatic beta cell function.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

Arnold M.Moses; Patricia Numann ; Myron Miller. Mechanism of chlorpropamide-induced antidiuresis in man: Evidence for release of ADH and enhancement of peripheral action. Metabolism. 1973, 22,(1), 59-66.

 

R.D.Leslie; D.A.Pyke. Chlorpropamide-alcohol flushing: a dominantly inherited trait associated with diabetes. Br Med J. 1978, 2,(6151), 1519-1521.

GHS Hazard and Precautionary Statements

Hazard Statements: H351-H302

Suspected of causing cancer. Harmful if swallowed.

Precautionary Statements: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2186
Harmonized Tariff Code
2935.00
TSCA
No
RTECS
YS6650000

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