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Azadibenzocyclooctyne-PEG4-NHS ester is applied for protein-peptide conjugation, peptide-small molecule conjugation, 18F radiolabeling, protein-oligonucleotide conjugation and surface modification.
Dingbin Liu; Jie Yang; He-Fang Wang; Zhongliang Wang; Xinglu Huang; Zhantong Wang; Gang Niu; A.R.Hight Walker; Xiaoyuan Chen. Glucose oxidase-catalyzed growth of gold nanoparticles enables quantitative detection of attomolar cancer biomarkers. Anal. Chem. 2014, 86,(12), 5800-5806.
Guoquan Li; Yan Xing; Jing Wang; Peter S.Conti; Kai Chen. Near-infrared fluorescence imaging of CD13 receptor expression using a novel Cy5.5-labeled dimeric NGR peptide. Amino Acids. 2014, 46,(6), 1547-1556.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant