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405060-95-9 - Salubrinal - eIF-2alpha Inhibitor - SAL - J64192 - Alfa Aesar

J64192 Salubrinal

CAS Number
405060-95-9
Synonyms
eIF-2alpha Inhibitor
SAL

Size Price ($) Quantity Availability
5mg 103.00
10mg 172.00
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Salubrinal

MDL
MFCD00548612

Chemical Properties

Formula
C21H17Cl3N4OS
Formula Weight
479.81
Form
Powder
Sensitivity
Light Sensitive
Solubility
Insoluble in water.

Applications

Salubrinal is a selective Inhibitor of eIF2α (eukaryotic translation initiation factor 2 α-subunit) dephosphorylation, inhibiting global protein translation. Salubrinal is a specific inhibitor of ER Stress induced apoptosis.

Notes

Light Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

David Kessel. Protection of Bcl-2 by salubrinal. Biochemical and Biophysical Research Communications. 2006, 346, (4), 1320-1323.

Yuta Komoike.; Hisako Inamura.; Masato Matsuoka. Effects of salubrinal on cadmium-induced apoptosis in HK-2 human renal proximal tubular cells. Archives of Toxicology. 2012, 86, (1), 37-44.

Other References

Harmonized Tariff Code
2933.49
TSCA
No

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