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178603-78-6 - Caspase-1 Inhibitor II - Ac-YVAD-CMK - IL-1beta Converting Enzyme (ICE) Inhibitor II - J64226 - Alfa Aesar

J64226 Caspase-1 Inhibitor II

Alfa Aesar offer differentially carbamylated low density lipoproteins (c-LDL). Carbamylated Human LDL is made with potassium cyanage. Each lot is analyzed for the degree of carbamylation (via diacetylmonoxime assay and the e-carbamyl-Lysine (homocitrulline) present versus native LDL in nanomoles/mg protein) and the c-LDL migration versus the native LDL on agarose gel electrophoresis. /n

CAS Number
178603-78-6
Synonyms
Ac-YVAD-CMK
IL-1beta Converting Enzyme (ICE) Inhibitor II

Size Price ($) Quantity Availability
5mg 227.00
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Caspase-1 Inhibitor II

MDL
MFCD00237124

Chemical Properties

Formula
C24H33ClN4O8
Formula Weight
540.99
Form
Powder

Applications

The low density lipoproteins carbamylated by urea has been postulated to have biologic effects relevant to atherosclerosis. Carbamylated LDL induces endothelial cell death and makes way for proliferation of smooth muscle cells. Traditional cardiovascular risk factors were not able to explain the presence of accelerated atherosclerosis in patients with kidney disease. Kidney patients have elevated urea which leads to carbamylation of proteins.

Notes

Store at 4°C for up to 3 months.

Other References

Harmonized Tariff Code
2924.19
TSCA
No
RTECS
AY3079566

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