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Sodium n-dodecyl sulfate is an anionic detergent used to function as a protein denaturant. It is mainly used in detergents for laundry with many cleaning applications. It finds application in the determination of protein molecular weight by polyacrylamide gel electrophoresis and in the analysis of hemoglobin. In food products, it is used as an emulsifying agent and a whipping aid. It is widely found in toothpastes, shampoos, shaving creams and bubble bath formulations due to its thickening effect and ability to create a lather.
Taheri-Kafrani, A., & Bordbar, A. K. Isothermal titration calorimetric study on the interaction of apo-human transferrin with sodium n-dodecyl sulfate. J. Therm. Anal. Calorim 2014, 115 (3), 2123-2127.
Chen, J.; Xue, H.; Yao, Y.; Yang, H.; Li, A.; Xu, M.; Chen, Q.; Cheng, R. Effect of Surfactant Concentration on the Complex Structure of Poly(N-isopropylacrylamide)/Sodium n-Dodecyl Sulfate in Aqueous Solutions. Macromolecules 2012, 45 (13), 5524-5529
Hazard Statements: H228-H302-H311-H315-H319-H335
Flammable solid. Harmful if swallowed. Toxic in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P210-P261-P280-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.