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53994-73-3 - Cefaclor - Panoral - (R)-3-Chloro-7-((S)-2-amino-2-phenylacetamido)-3-cephem-4-carboxylic acid - J64252 - Alfa Aesar

J64252 Cefaclor

CAS Number
53994-73-3
Synonyms
Panoral
(R)-3-Chloro-7-((S)-2-amino-2-phenylacetamido)-3-cephem-4-carboxylic acid

Size Price ($) Quantity Availability
1g 150.80
10g 326.51
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Cefaclor

MDL
MFCD00151471
EINECS
258-909-5

Chemical Properties

Formula
C15H14ClN3O4S
Formula Weight
367.81
Form
Powder
Solubility
Soluble in 1N HCl

Applications

Cefaclor is used to study urinary tract, intra-abdominal, and Haemophilus influenzae infections. It is used to study the mechanism of human renal organic anion and peptide transporters such as hOAT1, hPEPT1, and hPEPT2 and to study the effects of inhibition of penicillin-binding proteins on bacterial cell wall mucopeptide synthesis.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

C.O.Onyeji; D.P.Nicolau; C.H.Nightingale; R.Quintiliani. Optimal times above MICs of ceftibuten and cefaclor in experimental intra-abdominal infections. Antimicrobial Agents and Chemotherapy. 1994, 38,(5), 1112-1117.

 

Meng Li, Gail D.Anderson; Brian R.Phillips; Wei Kong; Danny D.Shen; Joanne Wang. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metabolism and Disposition. 2006, 34,(4), 547-555.

GHS Hazard and Precautionary Statements

Hazard Statements: H334-H317

May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.

Precautionary Statements: P285-P261-P280-P342+P311-P363-P304+P341-P321-P333+P313-P302+P352-P501a

In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. IF ON SKIN: Wash with plenty of soap and water. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1912
Beilstein
8176092
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
XI0363000

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