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27821-45-0 - Uridine-5'-diphosphate disodium salt, 98% - J64329 - Alfa Aesar

J64329 Uridine-5'-diphosphate disodium salt, 98%

CAS Number
27821-45-0
Synonyms

Size Price ($) Quantity Availability
100mg 54.00
500mg 247.20
1g 288.00
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Uridine-5'-diphosphate disodium salt, 98%

MDL
MFCD00149253
EINECS
248-678-9

Chemical Properties

Formula
C9H12N2Na2O12P2
Formula Weight
448.13
Form
Powder
Sensitivity
Moisture Sensitive
Solubility
Slightly soluble in water.

Applications

Uridine-5'-diphosphate disodium salt is used in studies on nucleic acid (RNA) biosynthesis and cell signaling. UDP is a nucleotide that upon phosphorylation to UTP becomes a substrate for enzymes such as RNA polymerase(s) and GTPases. These enzymes are involved in a wide range of applications from the synthesis of RNA to the regulation of G-coupled Protein Receptors (GPCR) and cell signaling molecules such as Rho-signaling via Guanine Nucleotide Exchange Factors (GEF).

Notes

Protect from heat. Store away from oxidizing agents.

Literature References

Ivar von Kugelgen.; Klaus Starke. Evidence for two separate vasoconstriction-mediating nucleotide receptors, both distinct from the P2X-receptor, in rabbit basilar artery: a receptor for pyrimidine nucleotides and a receptor for purine nucleotides. Naunyn-Schmiedeberg's Archives of Pharmacology. 1990, 341, (6), 538-546.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
8817400
Harmonized Tariff Code
2934.99
TSCA
No

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