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J64386 GM 6001, Negative Control

CAS Number
Synonyms
(N-t-Butoxycarbonyl-L-leucyl-L-tryptophan methylamide)

Stock No. Size Price ($) Quantity Availability
J64386-M^ 1mg 80.30
J64386-#0 5mg 280.00
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GM 6001, Negative Control

MDL
MFCD02683943

Chemical Properties

Formula
C23H34N4O4
Formula Weight
430.54
Form
Solid
Storage & Sensitivity
Store at -20°C. Moisture Sensitive.
Solubility
Soluble in DMSO

Applications

GM 6001 is a useful negative control for GM 6001. It is a cell permeable fibroblast collagenase inhibitor and antagonizes matrix metalloproteases (MMP) potentially involved in angiogenesis.

Notes

Following recosntitution, aliquot and store at -20°

Literature References

Martin A.Bruno; A.Claudio Cuello. Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade. Current Issue. 103, 103,(17), 6735-6740.

 

Diana Amantea; Rossella Russo; Micaela Gliozzi; Vincenza Fratto; Laura Berliocchi; G.Bagetta; G.Bernardi; M.Tiziana Corasaniti. Early upregulation of matrix metalloproteinases following reperfusion triggers neuroinflammatory mediators in brain ischemia in rat. International Review of Neurobiology. 2007, 82,149-169.

Hazard Statements:

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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