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GM 6001, Negative Control - (N-t-Butoxycarbonyl-L-leucyl-L-tryptophan methylamide) - J64386 - Alfa Aesar

J64386 GM 6001, Negative Control

CAS Number
Synonyms
(N-t-Butoxycarbonyl-L-leucyl-L-tryptophan methylamide)

Size Price ($) Quantity Availability
1mg 85.70
5mg 300.00
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GM 6001, Negative Control

MDL
MFCD02683943

Chemical Properties

Formula
C23H34N4O4
Formula Weight
430.54
Form
Solid
Sensitivity
Moisture Sensitive
Solubility
Soluble in DMSO

Applications

GM 6001 is a useful negative control for GM 6001. It is a cell permeable fibroblast collagenase inhibitor and antagonizes matrix metalloproteases (MMP) potentially involved in angiogenesis.

Notes

Following recosntitution, aliquot and store at -20°

Literature References

Martin A.Bruno; A.Claudio Cuello. Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade. Current Issue. 103, 103,(17), 6735-6740.

 

Diana Amantea; Rossella Russo; Micaela Gliozzi; Vincenza Fratto; Laura Berliocchi; G.Bagetta; G.Bernardi; M.Tiziana Corasaniti. Early upregulation of matrix metalloproteinases following reperfusion triggers neuroinflammatory mediators in brain ischemia in rat. International Review of Neurobiology. 2007, 82,149-169.

GHS Hazard and Precautionary Statements

Precautionary Statements: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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