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Prepared in rabbits using human LDL as the immunogen. Both human LDL and VLDL react with the antibody but not human HDL as determined via immunodiffusion and ELISA methods. The antibody is suitable for the immunohistochemical localization of LDL, Ac-LDL and Ox-LDL in cells or tissues.Anti-Human LDL antibody, from rabbit finds application in ELISA, flow cytometry, immunofluorescence and immunohistochemistry.
Le, Q. T.; Blanchet, M.; Seidah, N. G.; Labonté, P. Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9. J. Biol. Chem. 2015, 290 (38), 23385-23400.
Romagnuolo, R.; Scipione, C. A.; Boffa, M. B.; Marcovina, S. M.; Seidah, N. G.; Koschinsky, M. L. Lipoprotein(a) Catabolism Is Regulated by Proprotein Convertase Subtilisin/Kexin Type 9 through the Low Density Lipoprotein Receptor. J. Biol. Chem. 2015, 290 (18), 11649-11662.