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J64508 Bolton-Hunter Reagent

CAS Number
34071-95-9
Synonyms
N-Succinimidyl-3-(4-hydroxyphenyl)propionate
Rudinger reagent

Stock No. Size Price ($) Quantity Availability
J64508-03 1g 137.00
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Bolton-Hunter Reagent

MDL
MFCD00005515
EINECS
251-818-1

Chemical Properties

Formula
C13H13NO5
Formula Weight
263.25
Form
Powder
Melting point
132-133°
Storage & Sensitivity
Store at -20°C.
Solubility
Soluble in water.

Applications

Bolton-Hunter Reagent is used for iodination of proteins that do not contain tyrosine residues, Bolton-Hunter reagent precursor (3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester) is a hydroxysuccinimide ester used as an intermediate for high radioactive radioiodination of proteins.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Georges Gaudriault.; Jean-Pierre Vincent. Selective labeling of α- or ?-amino groups in peptides by the Bolton-Hunter reagent. Peptides. 1992, 13, (6), 1187-1192.

Carlier, M.F.; Simon, C.; Pantaloni, D. Radioiodination of brain tubulin with Bolton-Hunter reagent. Biochemical and Biophysical Research Communications. 1980, 96, (4), 1761-1767.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1545011
Harmonized Tariff Code
2928.00
TSCA
No

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