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PTP1B Inhibitor is used as a PTP1B inhibitor blocks the activity of the Protein Tyrosine Phosphatase 1B, which is a key factor in the negative regulation of insulin and leptin signaling pathway. Protein tyrosine phosphatase 1B (PTP1B) has critical roles in cell signaling relevant to diabetes, obesity, and cancer.
Sheng Zhang.; Zhong-Yin Zhang. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery. Drug Discovery Today. 2007, 12, (9-10), 373-381.