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J64581 Benserazide hydrochloride

CAS Number
14919-77-8
Synonyms
DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride

Stock No. Size Price ($) Quantity Availability
J64581-03 1g 76.40
J64581-06 5g 262.00
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Benserazide hydrochloride

MDL
MFCD00078571
EINECS
238-991-9

Chemical Properties

Formula
C10H15N3O5•HCl
Formula Weight
293.70
Form
Powder
Melting point
146-148°
Storage & Sensitivity
Keep Cold. Light Sensitive.
Solubility
Soluble in water, dimethyl sulfoxide and methanol. Insoluble in ethanol and acetone.

Applications

Inhibitor of L-aromatic amino acid decarboxylaseBenserazide hydrochloride is used as an antiparkinsonian. It is a peripheral decarboxylase inhibitor. It is used as an inhibitor for aromatic L-aminoacid decarboxylase. Further, it serves as an inhibitor of tyrosine hydroxylase (TH) and Tryptophan hydroxylase (TPH) inhibitor.

Notes

Incompatible with strong oxidizing agents.

Literature References

Terenteva, E. A.; Apyari, V. V.; Dmitrienko, S. G.; Zolotov, Y. A. Formation of plasmonic silver nanoparticles by flavonoid reduction: A comparative study and application for determination of these substances. Spectrochim. Acta, Part A 2015, 151, 89-95.

Ren, Z.; Yang, N.; Ji, C.; Zheng, J.; Wang, T.; Liu, Y.; Zuo, P. Neuroprotective effects of 5-(4-hydroxy-3-dimethoxybenzylidene)-thiazolidinone in MPTP induced Parkinsonism model in mice. Neuropharmacology 2015, 93, 209-218.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,1050
Harmonized Tariff Code
2928.00
TSCA
No
RTECS
VT9632300

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