8-Bromo-2'-deoxyguanosine is useful as the starting structure for 2'-deoxyguanosine nucleotides, which are modified in position 8.
Peter M. Gannett.; Tushar P. Sura. An Improved Synthesis of 8-Bromo-2'-deoxyguanosine. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 1993, 23 (11), 1611-1615.
Takumi Kimura.; Kiyohiko Kawai.; Sachiko Tojo.; Tetsuro Majima. One-Electron Attachment Reaction of B- and Z-DNA Modified by 8-Bromo-2-deoxyguanosine. J. Org. Chem. 2004, 69 (4), 1169-1173.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant