Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

364590-63-6 - Smoothened Agonist dihydrochloride dihydrate - SAG1.3 HCl - J64726 - Alfa Aesar

J64726 Smoothened Agonist dihydrochloride dihydrate

CAS Number
364590-63-6
Synonyms
SAG1.3 HCl

Size Price ($) Quantity Availability
1mg 126.69
5mg 349.60
Add to Cart Add to Quote Request View Item

Smoothened Agonist dihydrochloride dihydrate

MDL
MFCD14636155

Chemical Properties

Formula
C28H28ClN3OS•2HCl.2H2O
Formula Weight
599.00
Form
Solid
Sensitivity
Light Sensitive & Hygroscopic
Solubility
Soluble in water.

Applications

Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers. It is sensitive to light. It is hygroscopic in nature. Protect from humidity and water. Store under dry inert gas.

Other References

Harmonized Tariff Code
2934.99
TSCA
No

Recommended

  • J66563

    Neuropeptide S, mouse
  • L01102

    4-Ethylphenoxyacetic acid, 97%
  • H66040

    N-Fmoc-O-benzylphospho-L-tyrosine, 95%
  • 89895

    Strontium sulfide, 99.9% (metals basis)
  • 44157

    Bis(1,5-cyclooctadiene)nickel(0), 96%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware