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J65029 Lipoprotein, low density, acetylated, human plasma, 99%, BT-906

**Product Being Discontinued…Please See Below**

CAS Number
Synonyms
Ac-LDL
Acetylated LDL

Stock No. Size Price ($) Quantity Availability
J65029-8+ 2mg 189.00
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Lipoprotein, low density, acetylated, human plasma, 99%, BT-906

Chemical Properties

Form
Liquid
Storage & Sensitivity
Keep Cold.

Grade Specifications

We are discontinuing the lipoprotein reagents that are currently sold under the Alfa Aesar brand.

For future orders, Thermo Fisher Scientific offers high-quality lipoprotein reagents under the Invitrogen™ and Gibco™ brands.

The available replacement can be found here: Invitrogen™ Low Density Lipoprotein from Human Plasma, Acetylated (AcLDL)

Applications

Useful in the study of endothelial cells and microglia. Also useful as a positive control of foam cell formation.Lipoprotein, low density, acetylated, human plasma is used for receptor binding to murine peritoneal macrophages. Further, it is taken up by macrophage and endothelial cells that possess scavenger receptors specific for the modified LDL.

Notes

Supplied at 2mg/ml in 0.05M TRIS-HCl buffer, with 0.15M NaCl and 0.3mM EDTA, pH 7.4. Contains gentamicin sulfate. Aseptically packaged and sterile filtered. Store at 4°C. Do not freeze. Short shelf life: up to 3 months.

Literature References

Dai, Y.; Su, W.; Ding, Z.; Wang, X.; Mercanti, F.; Chen, M.; Raina, S.; Mehta, J. L. Regulation of MSR-1 and CD36 in macrophages by LOX-1 mediated through PPAR- 2013, 431 (3), 496-500.

Michael, D. R.; Davies, T. S.; Laubertová, L.; Gallagher, H.; Ramji, D. P. The Phosphoinositide 3-Kinase Signaling Pathway is Involved in the Control of Modified Low-Density Lipoprotein Uptake by Human Macrophages. Lipids 2015, 50 (3), 253-260.

Zhang, Y.; Han, Q.; You, S.; Cao, Y.; Zhang, X.; Liu, H.; Hu, L.; Liu, C. F. Rapamycin Promotes the Autophagic Degradation of Oxidized Low-Density Lipoprotein in Human Umbilical Vein Endothelial Cells. J. Vasc. Res. 2015, 52 (3), 210-219.

Other References

Harmonized Tariff Code
3002.19
TSCA
No

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